In 88% (36 out of 41) of patients with high-risk HPV, taking reishi + turkey tail mushrooms daily for 2 months cleared the virus, versus 5% clearance (1 out of 20) in the control group. I suspect that 88% clearance rate would be higher if they continued for longer than 2 months.
volkl48 10 hours ago [-]
Sorry, but no. This does not pass the smell test in the slightest.
This is:
- A single author paper with no academic affiliations.
- A search on the internet for this author finds them also pitching essential oils and a wide variety of other "alternative medicine" on the Youtube/Podcast grifter circuit and not the sorts of alternative medicine anyone seriously thinks might have some merit.
- The address listed for his supposed place of practice appears to be a roadside "clini-spa" advertising beauty treatments.
- This could only get published in some low-impact journal that's solely about the purported benefits of mushrooms, even though if true this would be a pretty revolutionary finding that would be of interest to far bigger journals.
Can I prove it's fraud? No, especially since I'm not paying $25 to look at the paper details.
But unless this finding replicates from someone with credibility, I don't think this means much of anything and I certainly don't think you should be taking anything in this paper as a fact.
bubblegumcrisis 11 hours ago [-]
[dead]
wxw 1 days ago [-]
Tangentially related, apparently xylitol gum can reduce cavity risk by killing off bacteria (which cannot digest but cannot differentiate xylitol from regular sugar) in the mouth.
mdasen 1 days ago [-]
Xylitol is really cool that way. The bacteria waste energy trying to convert it to a form they can use, but they just end up with at a dead end with xylitol-5-phosphate. Once they realize that they need to get rid of it, they convert it back to xylitol (so it can cross the membrane easier and probably to keep the phosphate). Of course, that means the xylitol is back to fool some other nearby bacteria into wasting its energy.
They end up wasting their energy on work that won't help them reproduce and needing to waste more energy getting rid of it.
1PlayerOne 16 hours ago [-]
I swish xylitol crystal after each meal for five minutes and then spit out. I no longer have plague on my lower bottom teeth, a problem area for most people. I like the fresh minty feel afterward as well. Wish I had learn about this earlier.
wuschel 21 hours ago [-]
Sounds interesting, indeed. Just dug up this review [1] that claims there were no adverse effects from any of the interventions, and that after 2.5 to 3 years of use, a fluoride toothpaste containing 10% xylitol may reduce caries by 13% when compared to a fluoride-only toothpaste.
I wonder how well bacteria will adapt long term in your mouth to Xylitol exposure through bubble gum based adminstration.
[1] Xylitol-containing products for preventing dental caries in children and adults. Cochrane Database of Systematic Reviews 2015, Issue 3. Art. No.: CD010743. DOI: 10.1002/14651858.CD010743.pub2.
morjom 19 hours ago [-]
Couldnt find any (relatively recent) studies that looked at bacteria over multiple years, but some earlier ones (1&2), or shorter period ones(3), that touch on it (aswell as caries, as that is the prevalent subject)
Not just gut flora. High levels of circulating xylitol (and erythritol for that matter) have been shown in both mouse models and humans to be associated with increased platelet reactivity and elevated 3-year risk of major cardiovascular events.
But we're talking significant levels of xylitol/erythritol, such as from keto-friendly ice cream and drinks, not the modest levels from chewing gum, and the dental benefits are well established.
GuB-42 14 hours ago [-]
It certainly is a problem for the guts of some people.
There is a hilarious Amazon review describing the effects of sugar-free gummy bears in rather graphic details.
It does? I wonder, what it does to the gut biome then
toasty228 22 hours ago [-]
It's already bad for your cardiovascular system. It's food as a mouth wash but don't swallow it, especially at the recommended doses of 3+ mouthwash per day with 3-5g each time
morjom 18 hours ago [-]
The recent study on it gave the subjects a 300mL "standardized, artificially sweetened beverage containing 30g of xylitol diluted in water."
Recommended amount is 5–10g per day (5 pieces of 100% xylitol gum, 36% is already effective), taken after meals.
spike021 23 hours ago [-]
Just be careful around dogs and presumably other pets as it's toxic for them.
nixonaddiction 15 hours ago [-]
apparently it helps reduce risk of mouth cancer..... what im hearing is rotate this and zyns in my mouth, see what happens.
noisy_boy 1 days ago [-]
Alternative form of delivery required for Singapore.
eru 19 hours ago [-]
Chewing gum in Singapore is a bit like medical marijuana was in California.
Possession and use of chewing gum is legal. Importation for personal consumption is also legal. Selling and importing in commercial quantities are banned.
whazor 17 hours ago [-]
Ah, a real delicacy then
kybishop 1 days ago [-]
I'm just over here wondering how/where/when I can buy this
VladVladikoff 1 days ago [-]
I wonder if chewing mastic would be as effective?
code_biologist 23 hours ago [-]
I started chewing mastic gum a few years ago as a jaw-shape maintenance measure. An encouragement for anyone who's curious about it: I like the taste and stiff texture of mastic more than normal gum these days.
hkt 22 hours ago [-]
Can you explain what you mean by a maintenance measure for your jaw shape? Is the idea.. a jaw workout?
code_biologist 19 hours ago [-]
The looksmaxxing thing is a real reason mastic gum as a jaw workout is promoted. Won't deny that.
My use of it comes from early 2010s era paleo-food community observations about hunter gatherers having less crowded jaws than agriculturalist and modern peoples, hypothesized to be due to both micronutrient intake and also eating tougher foods. Cramped jaws and facial structures lead to both malocclusion and also nasal breathing issues, and mouth breathing also reinforces those pathological facial changes. Granted, this stuff is from sources that I've heard wildly varying opinions on (Weston A Price; Mike Mew). Jaw and facial structure continues to change into adulthood. I needed extensive orthodontics in my youth and have struggled with sleep apnea in adulthood. This broad set of hypotheses made sense to me, and chewing mastic gum was the easiest way to get a full dose of "chew tougher food" in my life. I try to snack on raw carrots too.
Speaking to attractiveness, there's an uncomfortable photo of identical twins in one of the Weston Price books, one given orthodontic treatment that widened their facial structure and one was not. The one with the widened facial structure was more attractive. The difference wasn't gigantic, but it wasn't small either.
taurusnoises 18 hours ago [-]
I'm just hear to commiserate with the only person I've come across online in decades mentioning Weston A Price and his book of dental studies, which no doubt dates us. (The side-by-side jaw images left an impression on me as well). I'm guessing you were also part of the Price to Nourishing Traditions cookbook pipeline? Everyone I knew had at least the cookbooks back in the day.
Highly recommended, at minimum for interesting historical look at various cultures with a pre-modern processed food diet. AFAIK the basic hypothesis about diet affecting face morphology holds up.
4gotunameagain 22 hours ago [-]
It's the new gen Z and younger thing, micro-optimise your appearance.
Outcome of chronic social media exposure.
rustystump 22 hours ago [-]
it originated way earlier as a way to help people who have naturally small nasal passages. i guess both mewing and chewing help widen passages. The book breath goes into details but from the perspective of health and not looks. This has been known for like 100 years but mostly dentists payed attention to it.
The fact is mewing and chewing do make a measurable difference…over time. Tiktok promotes extremes as they get more views and the more extreme the more views in a cycle of escalation. This gave birth to sad boys who see the Toyota chivalre’s and think they need the same jawline. Similar sad nonsense has been going on for women too but that has unfortunately become all but normalized.
kevin_thibedeau 13 hours ago [-]
> Similar sad nonsense
It's amazing how they normalized fillers to the point of being hideous and convinced themselves that that's a beautiful aesthetic. The consensus seeking hive mind at work.
eru 19 hours ago [-]
I tried it, but it goes through some weird changes while you chew it.
jdw64 23 hours ago [-]
I'm curious. HIV has been largely conquered, so why hasn't HPV been conquered yet? Same goes for shingles.
kevin_thibedeau 13 hours ago [-]
Chicken pox is conquered. We went from 95% to <1%. Shingles will see a similar plunge.
Perseids 22 hours ago [-]
Adding to my sibling comments: It also has been conquered in some sense of the word. There are effective vaccines for the 9 most problematic HPV types: https://en.wikipedia.org/wiki/HPV_vaccine . It is worth getting, regardless of your gender.
cubefox 19 hours ago [-]
Gardasil 9 seems to be the best available HPV vaccine. I guess the chewing gum is mainly intended for people who were already infected with some HPV strain before they got the vaccine, or where the vaccine didn't work (because it doesn't offer complete protection).
AlanYx 13 hours ago [-]
>Gardasil 9 seems to be the best available HPV vaccine.
Only in high income countries. The 4-valent version is still the dominant version available worldwide.
cubefox 11 hours ago [-]
For Gardasil 9, some lower income countries also use just a single dose rather than two, due to cost.
cyberax 22 hours ago [-]
You need to use antiretrovirals constantly to control the HIV. It's not worth it for the HPV that is mostly benign (and only rarely causes cancer).
jdw64 22 hours ago [-]
thanks!
jobs_throwaway 14 hours ago [-]
There's been a lot of failed attempts at therapeutic vaccines and the like, but nothing has proven effective. It seems that the virus is quite hard to detect and target in the skin.
That, plus a lack of urgency due to the effectiveness of preventative vaccines, leads to a lack of urgency on the issue.
TZubiri 22 hours ago [-]
Less resources devoted to curing because of lower lethality
bamboozled 19 hours ago [-]
This is the future I wanted.
fuckyah 17 hours ago [-]
[dead]
shevy-java 1 days ago [-]
Sounds like an ad. "Eat this gum, it is so healthy."
stogot 1 days ago [-]
Gum is often made of plastics so won’t be surprised if cancerous themselves
fernly 1 days ago [-]
It says, "involving chewing gum made from lablab beans (bean gum)".
Taiwanese researchers found that a carbohydrate-binding protein (i.e. a legume lectin) from lablab beans effectively blocks the infections of influenza viruses and SARS-CoV-2.[60] Researchers from Finland and USA found that extracts from chewing gum manufactured from lablab bean seeds had broad-spectrum anti-viral properties, likely due to the binding action of Flt3 Receptor Interacting Lectin (FRIL) on viruses; the anti-viral effect was similar to that of purified FRIL
jerbearito 1 days ago [-]
Lol they didn't read the article.
dyauspitr 1 days ago [-]
Hunh I always assumed it was just some kind of modified natural rubber but it’s literally plastic (PVAc, PIB) that release microplastics into the saliva.
nomel 1 days ago [-]
Not all is, including the one mentioned in the article. There are many "natural" chewing gum brands, that use plant based gum. You can buy boxes Amazon, or usually find them in the candy aisle of higher end grocery stores. You're probably not going to find it in a gas station/convenient store.
colordrops 21 hours ago [-]
Aren't all gum based basically plastic? Including natural ones? So chewing any gum is just going to fill your body with microplastics right? I wonder if the risk offset is worth it.
Not worth the time of day until it can be demonstrated that there is a net health benefit. Precautionary Principle FTW.
fsckboy 1 days ago [-]
humans evolved to have risk seekers and risk avoiders. some people try it, the other people watch.
skylurk 23 hours ago [-]
we owe the dairy industry to this phenomena, and also a lot of fetishes
rustystump 22 hours ago [-]
I mean some fetishes have science behind why they exist. For example, the part of the brain that process feet is located next to the area that processes genitals. At least, some are explainable. Some are not.
eru 19 hours ago [-]
Well, if natural selection had a say, the only fetish anyone would have would be an impregnation fetish. (Only half joking.)
fyltr 18 hours ago [-]
Natural selection had a say in female mammals leaking blood trails every month, which is, mildly said, fcking stupid. Natural selection does not create optimal beings, it creates stuff that, somehow, kinda, works.
If you have the time for it, I highly recommend the lecture series on behavioral evolution by Robert Sapolsky, it's on the Stanford YouTube channel.
Benanov 15 hours ago [-]
It's stupid from a practical perspective but the energy required to build up the uterine lining and tear it down on a (basically-)monthly basis is much lower than its upkeep
Rendered at 05:08:58 GMT+0000 (Coordinated Universal Time) with Vercel.
https://pubmed.ncbi.nlm.nih.gov/25271984/
In 88% (36 out of 41) of patients with high-risk HPV, taking reishi + turkey tail mushrooms daily for 2 months cleared the virus, versus 5% clearance (1 out of 20) in the control group. I suspect that 88% clearance rate would be higher if they continued for longer than 2 months.
This is:
- A single author paper with no academic affiliations.
- A search on the internet for this author finds them also pitching essential oils and a wide variety of other "alternative medicine" on the Youtube/Podcast grifter circuit and not the sorts of alternative medicine anyone seriously thinks might have some merit.
- The address listed for his supposed place of practice appears to be a roadside "clini-spa" advertising beauty treatments.
- This could only get published in some low-impact journal that's solely about the purported benefits of mushrooms, even though if true this would be a pretty revolutionary finding that would be of interest to far bigger journals.
Can I prove it's fraud? No, especially since I'm not paying $25 to look at the paper details.
But unless this finding replicates from someone with credibility, I don't think this means much of anything and I certainly don't think you should be taking anything in this paper as a fact.
They end up wasting their energy on work that won't help them reproduce and needing to waste more energy getting rid of it.
I wonder how well bacteria will adapt long term in your mouth to Xylitol exposure through bubble gum based adminstration.
[1] Xylitol-containing products for preventing dental caries in children and adults. Cochrane Database of Systematic Reviews 2015, Issue 3. Art. No.: CD010743. DOI: 10.1002/14651858.CD010743.pub2.
https://pubmed.ncbi.nlm.nih.gov/2758793/
https://pubmed.ncbi.nlm.nih.gov/1810656/
https://www.frontiersin.org/journals/nutrition/articles/10.3...
But we're talking significant levels of xylitol/erythritol, such as from keto-friendly ice cream and drinks, not the modest levels from chewing gum, and the dental benefits are well established.
There is a hilarious Amazon review describing the effects of sugar-free gummy bears in rather graphic details.
https://old.reddit.com/r/funny/comments/1ktb95/most_helpful_...
I don't know if it is xylitol, but if not, it is another sugar alcohol, like sorbitol, maltitol, erythritol,... that have similar properties
not only xylitol, but sorbitol, mannitol and maltitol. Also related are lactose, fructose, and *saccharides.
the keyword is FODMAP, look up low-FODMAP diet.
maybe: https://www.med.unc.edu/medicine/gi/faculty-staff-website/wp...
Recommended amount is 5–10g per day (5 pieces of 100% xylitol gum, 36% is already effective), taken after meals.
Possession and use of chewing gum is legal. Importation for personal consumption is also legal. Selling and importing in commercial quantities are banned.
My use of it comes from early 2010s era paleo-food community observations about hunter gatherers having less crowded jaws than agriculturalist and modern peoples, hypothesized to be due to both micronutrient intake and also eating tougher foods. Cramped jaws and facial structures lead to both malocclusion and also nasal breathing issues, and mouth breathing also reinforces those pathological facial changes. Granted, this stuff is from sources that I've heard wildly varying opinions on (Weston A Price; Mike Mew). Jaw and facial structure continues to change into adulthood. I needed extensive orthodontics in my youth and have struggled with sleep apnea in adulthood. This broad set of hypotheses made sense to me, and chewing mastic gum was the easiest way to get a full dose of "chew tougher food" in my life. I try to snack on raw carrots too.
Speaking to attractiveness, there's an uncomfortable photo of identical twins in one of the Weston Price books, one given orthodontic treatment that widened their facial structure and one was not. The one with the widened facial structure was more attractive. The difference wasn't gigantic, but it wasn't small either.
Highly recommended, at minimum for interesting historical look at various cultures with a pre-modern processed food diet. AFAIK the basic hypothesis about diet affecting face morphology holds up.
Outcome of chronic social media exposure.
The fact is mewing and chewing do make a measurable difference…over time. Tiktok promotes extremes as they get more views and the more extreme the more views in a cycle of escalation. This gave birth to sad boys who see the Toyota chivalre’s and think they need the same jawline. Similar sad nonsense has been going on for women too but that has unfortunately become all but normalized.
It's amazing how they normalized fillers to the point of being hideous and convinced themselves that that's a beautiful aesthetic. The consensus seeking hive mind at work.
Only in high income countries. The 4-valent version is still the dominant version available worldwide.
That, plus a lack of urgency due to the effectiveness of preventative vaccines, leads to a lack of urgency on the issue.
https://en.wikipedia.org/wiki/Lablab --
Taiwanese researchers found that a carbohydrate-binding protein (i.e. a legume lectin) from lablab beans effectively blocks the infections of influenza viruses and SARS-CoV-2.[60] Researchers from Finland and USA found that extracts from chewing gum manufactured from lablab bean seeds had broad-spectrum anti-viral properties, likely due to the binding action of Flt3 Receptor Interacting Lectin (FRIL) on viruses; the anti-viral effect was similar to that of purified FRIL
HN is pretty good normally, but it has its share of idiots too.
https://samueli.ucla.edu/bursting-your-bubble-chewing-gum-re...
https://samueli.ucla.edu/bursting-your-bubble-chewing-gum-re...
This includes natural gum bases.